Free Ebook Forensic DNA Typing: Biology, Technology, and Genetics of STR MarkersBy John M. Butler
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Forensic DNA Typing: Biology, Technology, and Genetics of STR MarkersBy John M. Butler
Free Ebook Forensic DNA Typing: Biology, Technology, and Genetics of STR MarkersBy John M. Butler
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Since the enormously successful first edition of Forensic DNA Typing was published, the Human Genome Project has published a draft sequence of the human genome and completed the “finished” reference sequence. The advent of modern DNA technology has resulted in the increased ability to perform human identity testing—desirable in a number of situations including the determination of perpetrators of violent crime such as murder and rape, resolving unestablished paternity, and identifying remains of missing persons or victims of mass disasters. The technology has been utilized in identifying remains from victims of the World Trade Center twin towers collapse following the terrorist attacks of September 11, 2001, the President Clinton-Monica Lewinsky scandal, and the identification of the remains in the Tomb of the Unknown Soldier. Indeed, our perceptions of history have been changed with DNA evidence that revealed Thomas Jefferson fathered a child by one of his slaves. This book examines the science of current forensic DNA typing methods by focusing on the biology, technology, and genetic interpretation of short tandem repeat (STR) markers, which encompass the most common forensic DNA analysis methods used today. Ten new chapters have been added to accommodate the explosion of new information since the turn of the century.
*The only book available that specifically covers detailed information on mitochondrial DNA and the Y chromosome
*Chapters cover the topic from introductory level right up to "cutting edge" research
*High-profile cases are addressed throughout the book, near the sections dealing with the science or issues behind these cases
*NEW TO THIS EDITION: D.N.A. Boxes--boxed "Data, Notes & Applications" sections throughout the book offer higher levels of detail on specific questions
- Sales Rank: #1300305 in eBooks
- Published on: 2005-02-08
- Released on: 2005-02-08
- Format: Kindle eBook
Review
“When they write the history of forensic science for our times, Forensic DNA Typing will be cited as the classic text on the subject. John Butler’s organizational and communication skills have created a book unsurpassed in its abilities to guide a reader through the principles and practices of this complex but critical subject. This book is must reading for forensic educators and their students, and requires a prominent place on the shelf of every forensic and legal practitioner.”―Richard Saferstein, Ph.D., Author and Forensic Science Consultant
“The much-anticipated second edition of Dr. John Butler's Forensic DNA Typing provides an enormous amount of new and valuable information about DNA typing and the issues associated with this technology. It is a ‘must read’ for scientists, lawyers, academics, students, police officers or anyone who wants to understand modern DNA testing and the ways in which it has transformed criminal justice systems in the United States and around the world.”―Stephen Hogan, Esq., Instructor, Forensic Biology, SUNY-Albany; Faculty Member, DNA Forensics Program, American Prosecutors Research Institute
...it will be clear that the book is an exceptionally comprehensive reference, touching on every relevant aspect of current forensic DNA typing practice. Apart from coverage, the book is well edited, attractively laid out, and makes productive use of its four-color format. Abundant figures and tables help explain and enumerate basic concepts as needed. A feature that is found in several parts of the book that I found particularly appealing is the detailed sourcing of information. This is a very good book, and will serve many practitioners and students of forensic DNA typing as a single source reference. It could also serve as a text for a one semester graduate level course in forensic DNA typing and technology. It is hard to think of a topic in forensic DNA typing that is not treated in the book. Accordingly, it will be a sort of standard reference book in the area. If there are plans to keep the book up to date every few years, it has the potential to become the standard reference, perhaps something akin to Clarke in drugs and toxicology. A final point is that the book is a phenomenal bargain in this day and age at around $80 a copy. There are probably minor things about which one could quibble, but it doesn’t seem productive to do so when the overall product is so good. - Journal of Forensic Sciences
“Students, lecturers and laboratory workers will all welcome this new edition. At 660 pages it is double the size of the former edition and clearly contains a great deal of new material as well as having been re-arranged. Dr. Butler’s book goes far beyond dealing just with high profile cases and mass disasters. He has taken the opportunity in the expanded volume to explain all aspects of DNA typing in greater detail and has produced a volume which is not only informative but high readable. It is as much a book to be enjoyed by the scientist as one to educate and inform. This is a volume which contains something of value to all forensic scientists. It does not talk down to the reader but serves as a balanced guide through the rapidly developing field of DNA studies. It is a book that should be purchased rather than borrowed or just referred to as it is an outstanding guide to the subject. – Journal of Clinical Forensic Medicine
From the Back Cover
Since it was first used in a criminal investigation in 1986, forensic DNA testing has become not only one of the most high profile tools available to the legal system, but also one with a very high degree of confidence. The use of DNA testing has helped determine the perpetrators of violent crimes, resolve questioned paternity and identify the remains of missing persons or victims of mass disasters.
John Butler has been involved, first in the validation of the short tandem repeat (STR) markers that form the basis of the FBI's nation-wide DNA database (CODIS) and, lately, in the development of new and innovative technologies that may influence the future of the field. If you are involved with forensic DNA testing in any way, you cannot afford not to own this book.
Short tandem repeat loci will be the most widely used markers in forensic DNA analysis for many years to come, and suitable information on STR typing is needed for crime laboratory personnel as well as members of the legal community. This book examines the science of current DNA typing methods by focussing on the biology and technology behind STR markers and the most common forensic DNA analysis methods used today.
Features:
* Chapters cover the topic from introductory level right up to "cutting edge" research
* Forensic scientists learn about the new methods and technologies required by STR typing
* DNA laboratories find out how to meet the training requirements of the DNA Advisory Board Quality Assurance Standards (listed in Appendix III).
* Lawyers and law enforcement professionals understand the science behind the techniques
* Information listed on suppliers of DNA analysis equipment, products and services
About the Author
John M. Butler is a NIST Fellow and Special Assistant to the Director for Forensic Science, Office of Special Programs, at the U.S. National Institute of Standards and Technology, in Gaithersburg, Maryland. Dr. Butler earned his PhD from the University of Virginia while doing DNA research in the FBI Laboratory's Forensic Science Research Unit. He has won numerous scientific awards, including being named Science Watch’s #1 world-wide high-impact author in legal medicine and forensic science over the last decade (July 2011). He has over 150 publications in this field and is a frequent presenter on the topic of DNA typing, and has authored four other DNA Typing books including Advanced Topics in Forensic DNA Typing: Methodology. For a detailed CV, visit http://www.cstl.nist.gov/strbase/butler.htm.
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